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trends timeline for 5,10-%E3%83%A1%E3%83%81%E3%83%AC%E3%83%B3%E3%83%86%E3%83%88%E3%83%A9%E3%83%92%E3%83%89%E3%83%AD%E3%83%A1%E3%82%BF%E3%83%8E%E3%83%97%E3%83%86%E3%83%AA%E3%83%B3%E3%83%AC%E3%83%80%E3%82%AF%E3%82%BF%E3%83%BC%E3%82%BC%20-%205,10-methylenetetrahydromethanopterin%20reductase