Label: TEMOZOLOMIDE capsuleRECENT MAJOR CHANGESINDICATIONS AND USAGEDOSAGE AND ADMINISTRATIONDOSAGE FORMS AND STRENGTHSCONTRAINDICATIONSWARNINGS AND PRECAUTIONSADVERSE REACTIONSUSE IN SPECIFIC POPULATIONSFULL PRESCRIBING INFORMATION: CONTENTS*1 INDICATIONS AND USAGE2 DOSAGE AND ADMINISTRATION3 DOSAGE FORMS AND STRENGTHS4 CONTRAINDICATIONS5 WARNINGS AND PRECAUTIONS6 ADVERSE REACTIONS8 USE IN SPECIFIC POPULATIONS10 OVERDOSAGE11 DESCRIPTION12 CLINICAL PHARMACOLOGY13 NONCLINICAL TOXICOLOGY14 CLINICAL STUDIES15 REFERENCES16 HOW SUPPLIED/STORAGE AND HANDLING17 PATIENT COUNSELING INFORMATION
Experimental and Therapeutic Medicine Metronomic treatment of temozolomide increases anti-angiogenicity accompanied by down-regulated O6-methylguanine-DNA methyltransferase expression in endothelial cells