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trends timeline for 3-%E3%83%92%E3%83%89%E3%83%AD%E3%82%AD%E3%82%B7-2-%E3%83%A1%E3%83%81%E3%83%AB%E3%83%96%E3%83%81%E3%83%AA%E3%83%ABCoA%E3%83%87%E3%83%92%E3%83%89%E3%83%AD%E3%82%B2%E3%83%8A%E3%83%BC%E3%82%BC%20-%203-hydroxy-2-methylbutyryl-CoA%20dehydrogenase