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mTOR Inhibitors in Advanced Biliary Tract CancersAn Interplay Between Autophagy and Immunometabolism for Host Defense Against Mycobacterial InfectionmTor pathwayAdapting the Stress Response: Viral Subversion of the mTOR Signaling PathwayBiological Aspects of mTOR in LeukemiaThe many faces of mTOR and rapamycinBesides rapamycin itself, a number of other substances to varying degrees also inhibit mTOR signaling. Some of the newer substances are reported in publications such as (2008) A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis, (2008) Palomid 529, a novel small-molecule drug, is a TORC1/TORC2 inhibitor that reduces tumor growth, tumor angiogenesis, and vascular permeability, (2009) Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTO and (2009) Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. Some of these alternative substances are selective in whether they affect mTORC1 or mTORC2. And they may vary also in toxicity and secondary effects.Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain FunctionExperimental and Therapeutic Medicine PI3K/AKT/mTOR signalling pathway involvement in renal cell carcinoma pathogenesis (Review)The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT SignalingmTOR Pathway in Gastroenteropancreatic Neuroendocrine Tumor (GEP-NETs)InternationalJournal ofOncologyMetformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signalingPI3K/AKT/mTOR Signaling Regulates the Virus/Host Cell Crosstalk in HPV-Positive Cervical Cancer Cells
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enMTOR
esDiana de rapamicina en células de mamífero
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