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RNAポリメラーゼI

Mushroom Photograph - Rna Polymerase Inhibition Complex by Laguna Design/science Photo LibraryProtein SynthesisRNA polymeraseProkaryotic TranscriptionGE23077 binds to the RNA polymerase ‘i’ and ‘i+1’ sites and prevents the binding of initiating nucleotides Transcription inhibition by the depsipeptide antibiotic salinamide A Antibiotics: A new spanner in the works of bacterial transcription SIMMER employs similarity algorithms to accurately identify human gut microbiome species and enzymes capable of known chemical transformationsKonkontangikgzqRNA PolymeraseThe potential role of miRNAs in the pathogenesis of testicular germ cell tumors - A Focus on signaling pathways interplayRNA TranscriptionSandwalkRNAポリメラーゼ1、2、3の違いE.coli rna polymeraseRNA-dependent RNA polymerase moleculeImage result for dna polymerase 1T7 RNA PolymeraseDarstellung des Enzyms Reverse Transkriptase von HIV (humanes Immundefizienzvirus), das mit einem Molekül von DNA (Desoxyribonukleinsäure, blaue Helix) komplexiert ist. Die Reverse Transkriptase transkribiert das einsträngige RNA-Genom (Ribonukleinsäure) von HIV in DNA, das sich in einer menschlichen Zelle mit DNA integrieren kann.遺伝を担う生命維持に必須の酵素、立体構造を解明　理研、がん・ウイルス感染症の治療に期待Аналитические растворы «АЛМАСС Нео» для определения врожденных заболеваний обмена веществ у новорожденных методом ВЭЖХ-МС/МС25.2: RNA ProcessingWhat is the role of Bst DNA polymerase in LAMP?What is the role of Bst DNA polymerase in LAMP?真核生物のＤＮＡ複製Rnaポリメラーゼiiのc末端ドメインはlcドメインにより形成された可逆性のポリマー線維と結合しリン酸化により解離する ライフサイエンス 新着論文レビューRNA polymerase, the SARS-CoV-2 “sloppy photocopier”Perbezaan antara polimerase rna 1, 2 dan 3RNA polymeraseTranscriptionRna processing Rna processingDifference Between RNA Polymerase 1 2 3 - Comparison SummarySt. CharlesSammenligning mellem: DNA-polymerase Vs RNA-polymeraseStructure of RNA-dependent RNA polymerase from 2019-nCoV, a major antiviral drug targetCoronavirus disease 2019 (COVID-19), caused by 2019-nCoV, is spreading rapidly across the world and has been announced as a “global pandemic” by the World Health Organization (WHO) on 15 March 2020. According to the WHO, there are over 200,000 confirmed cases and more than 8,600 deaths in 166 countries, areas or territories (last updated by WHO on 18 March 2020 18:00 CET, https://experience.arcgis.com/experience/685d0ace521648f8a5beeeee1b9125cd). The 2019-nCoV is a new member of the betacoronavirus genus and closely related to severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). A 2019-nCoV infection generally causes flu-like symptoms, such as fever, dry cough and fatigue. Severe cases may progress to multi-organ failure and even death. Unfortunately, there is no vaccine or specific medicine to prevent or treat COVID-19 at present. Nonetheless, an antiviral drug candidate named remdesivir (development code GS-5734), originally developed for treating the Ebola patients, was considered as one of the most promising candidates based on its broad antiviral spectrum (https://apps.who.int/iris/bitstream/handle/10665/330680/WHO-HEO-RDBlueprint%28nCoV%29-2020.1-eng.pdf?ua=1).Coronaviruses employ a multi-subunit replication/transcription machinery, comprising of a set of non-structural proteins (nsp) produced as cleavage products of the ORF1a and ORF1ab viral polyproteins to facilitate virus replication and transcription. The RNA-dependent RNA polymerase (RdRp, also named nsp12), which catalyzes the synthesis of viral RNA, is a key component of coronaviral replication/transcription machinery and a primary target for the antiviral drug, remdesivir. Due to the crucial function of nsp12, the characterization of its structure in complex with its cofactors nsp7 and nsp8 provides atomic-level information to facilitate rational antiviral drug design and development.RNA Polymerase: Properties, Structure, Types, FunctionsRNA polymerase moleculeFigure_09_03_03.jpgwww.frontiersin.org
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