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Dr.Web

Data definition language#DROP statement

DVD Shrink

DVD Player (macOS)

DWARF

Oracle E-Business Suite

EAR (file format)

EasyBeans

Eclipse Modeling Framework

Ecu.test

European Institute for Computer Antivirus Research

EICAR test file

EISPACK

Elixir (programming language)

EMM386

Emmet (software)

Endorphin (software)

Jakarta Enterprise Beans

Envoy (WordPerfect)